Matt and Sarah et al. show 133 PKs in O. tauri (BMC Genomics 2014)

Laura et al. showed flexible timing across species (New Phytol. 2014) + data in BioDare, 10 models in PlaSMo.

Tomasz and Anne compared 6 period analysis methods (PLosone 2014),
all now online on BioDare, with step by step protocols (Meth. Mol. Biol. 2014)

Daniel and Alexandra's clock-regulated starch degradation (JRS Interface 2013), with models in PlaSMo.

ROBuST project identifies HOS1 as a clock gene (Plant Cell)

ROBuST models rhythmic CBF cold pathways (Plant Journal).

CK1 is a clock-affecting kinase in the green lineage, PLoSone and BMC Cell Bio 2013

ROBuST temperature-compensated clock model predicts LHY regulation, Mol Syst Biol 2013.

Alexandra's P2012 clock model explains TOC1 function and ABA input, BMC Sys Bio 2013.

Andrea's machine learning suggests repressilator in Ostreococcus, Bioinformatics 2013

Elisa's work shows Ostreococcus plasticity varies with location not relatedness, Nature Climate Change 2013

Congratulations to Gerben van Ooijen, starting his lab as Royal Society Fellow.

Gerben's review of non-transcriptional timing published in TiBS 2012

Video protocol for Ostreococcus transformation published in JoVE 2012

Coupled clocks make spatio-temporal waves, in PNAS 2012. Numerical data are public in BioDare

Non-transcriptional clock marker shared across all domains of Life, in Nature 2012

Flowering model's predicted function of FKF1 is validated, in Science 2012

Clock model's predicted function of TOC1 is validated, in Science 2012

Extended model finds repressilator in the plant clock, in Mol. Syst. Biol. 2012

has a new logo, from 2012

Jan 2012: CSBE becomes SynthSys, led by Prof. Vincent Danos (Director)

Andrew Millar elected to EMBO membership (2011) and Fellowship of the Royal Society (2012)

Shotgun proteomics identifies 27% of Ostreococcus proteins, LeBihan et al J Proteomics 2011

became part of SynthSys in Jan 2012

The proteasome is dispensable for non-transcriptional timing, but essential for the normal clock system, van Ooijen et al Current Biology 2011

A non-transcriptional clock in Ostreococcus O'Neill et al. Nature 2011 (and in red blood cells!)

9 papers in the first three months of 2011 - please see bibliography

Data from our 2010 papers and data curated from the literature is available here.

Plant clock model predicts function of PRR5 gene, Pokhilko et al Mol Syst Biol 2010.

Data and analysis show how the plant clock adjusts to day length, Edwards et al Mol Syst Biol 2010.

FP6 project ended in 2011

Store private SBML models after optimisation with SBSI's new plugin to the PlaSMo model database.

A fungal (Neurospora) clock model in the Bio-PEPA stochastic process algebra, Link.

Regulatory flexibility can confer robustness to biological clocks, Akman et al. BMC Syst Biol 2010.

CSBE's Systems Biology Software Infrastructure (SBSI) offers SBML model optimisation, tested on clock models.

TiMet - EU FP7-funded project studies how the plant circadian clock times metabolism.

Andrew passed on the GARNet P.I. role in Jan 2010

Models and timeseries data are available for the Arabidopsis photoperiod sensor from Salazar et al. Cell 2009, from the PlaSMo database of multiscale XML models.

Congratulations on your Ph.D., Dr. Oxana Sorokina- second to graduate from the Edinburgh lab.

Modelling the photoperiod switch in plants predicts new role for FKF1. Salazar et al. Cell 2009

Simulated evolution shows how multiple-loop circuits contribute to timing. Troein et al. Current Biology 2009

A light-emitting light switch in yeast, from EUClock! Sorokina et al. Journal of Biological Engineering 2009, 3:15.

A novel machine learning algorithm applied to plant circadian data: Grzegorczyk et al. "Modelling non-stationary gene regulatory processes with a non-homogeneous Bayesian network and the allocation sampler". Bioinformatics 2008.

Synthetic Biology Standards network was launched, June 2008

New software for sensitivity analysis of oscillator models, from Warwick (supersedes older IRC analysis).